(865) 999-5988 Request a Call
HomeWhat We Treat › Peyronie's

Non-Surgical Peyronie's Disease Treatment in Knoxville, TN

Discreet, non-surgical treatment for Peyronie's disease — no medications, no injections, no surgery.

4.7 stars from 273 patients Physician-Reviewed

See If You're a Candidate

Same business day callbacks Mon–Fri. No referral required.

By submitting you agree to be contacted by phone about your inquiry. See our Privacy Policy.

The short answer on Peyronie's disease

Low-Dose Radiation Therapy targets the inflammation of the active, early phase of the condition, when pain and change are still progressing. It is aimed at the inflammatory stage rather than at correcting a stable, long-established deformity.

How the treatment actually works

Course of treatment
A personalized plan
Each visit
About 15 minutes
Anesthesia
None
Downtime
None — you drive yourself home
Referral
Not required

Likely a fit Early disease with pain and ongoing change, ideally within the first year of symptoms.

Probably not a fit Stable, long-standing disease with no pain and no further change — a urologist is the right next conversation there.

See if Peyronie's disease is something we can treat

Is Low-Dose Radiation Therapy safe?

The dose used for benign conditions is a small fraction of cancer-treatment radiation — roughly 10–25× lower — delivered in a few short sessions. Low-dose radiation therapy for benign disease has decades of clinical use, and side effects are uncommon and typically mild.

Every treatment plan is prepared by a board-certified medical physicist and reviewed by a licensed physician. Whether it's the right option for you — and any personal considerations — is decided together during your consultation.

Is it covered? See accepted plans › Who would treat me? Meet the team ›

Our Approach

Low-dose radiation therapy is a non-surgical option that targets the inflammatory scar tissue (plaque) that forms in Peyronie's disease. It is a painless procedure that involves no medications, surgery, or needles. Published series report outcomes comparable to injection-based approaches.

Contact us to learn more about our Peyronie's treatment at our medical centre in Knoxville, TN.

Frequently Asked Questions: Peyronie's & LDRT

Can low-dose radiation therapy help Peyronie’s disease?

It is used during the active, inflammatory phase — the earlier stage when there is discomfort and the condition is still changing. Low-dose radiation therapy is aimed at calming that inflammation. It is not a way to reverse a change in shape that has already settled and matured; that is a structural issue better discussed with a urologist. Individual results vary.

Is there a non-surgical treatment for Peyronie’s disease?

There are several non-surgical approaches, and which ones are reasonable depends on how far along the condition is. Low-dose radiation therapy is one option during the active, uncomfortable phase. Once things have stabilized, both non-surgical and surgical options are best reviewed with a urologist. No single approach suits everyone, and every other option stays open.

What is the difference between the active and stable phase of Peyronie’s disease?

In the active, inflammatory phase the tissue is still irritated — there is often discomfort and the shape may still be changing from week to week, sometimes over many months. In the stable phase the inflammation has settled, discomfort usually fades, and the shape stops changing. Treatments that work by calming inflammation are relevant during the active phase, which is why knowing where you are matters more than the label.

Is it too late to treat my Peyronie’s disease?

That depends on whether the condition is still active. If you still have discomfort, or the shape seems to be changing, the inflammatory phase may still be open. If the discomfort passed a long time ago and nothing has changed since, that window has likely closed, and a urologist is the right person to discuss what remains available. It is worth asking rather than assuming.

Is low-dose radiation therapy safe for Peyronie’s disease?

The dose is a small fraction of the dose used to treat cancer and is directed at a limited area. Low-dose radiation therapy has been used for benign, non-cancerous conditions for decades. Side effects are uncommon and are usually mild and temporary, such as short-lived skin irritation. Any decision should be made with a clinician who has reviewed your situation.

Do I need a referral?

No. You can call us directly. If you have an orthopedic surgeon, primary care physician, or rheumatologist, we coordinate with them.

Does it hurt?

No. You feel nothing during treatment. No needle, no injection, no anesthesia.

Are there side effects?

Rare. Some patients notice mild, temporary skin redness. No systemic side effects.

Will it cause cancer?

The dose used for benign conditions is 10 to 25 times lower than the dose used to treat cancer. Long-term studies in Germany — where LDRT has been used for decades — have not shown an increased cancer risk at these low doses. We do not treat patients under 40 except in specific circumstances.

How quickly will I feel better?

Most patients begin noticing relief between 6 and 12 weeks after their final session. About 70% report meaningful improvement.

How long does relief last?

Typically 12 to 24 months. A second course can be given if symptoms return.

What if it doesn't work for me?

Most patients respond well — and if your consultation shows you're not a strong candidate, we'll tell you up front, before you've spent a dime. LDRT also never closes any doors: every other option, including surgery, stays open to you.

Is it covered by insurance?

Most major insurance is accepted, including Medicare and major commercial plans. Our office handles all insurance pre-authorization.

How many sessions will I need?

Most benign musculoskeletal conditions require 6 to 8 weekday sessions, scheduled on consecutive business days so you complete a full course in under two weeks. Each session takes about 15 minutes. Some skin and fibrotic conditions follow different protocols — your consultation will clarify what fits your situation.

Working With Your Care Team

Your urologist knows your history and your options better than anyone. We don't replace them, and we wouldn't want to. We're a resource for them — for patients who want a non-surgical, drug-free option before considering surgery. You stay in their care: we treat only what's referred, keep your doctors informed, and refer you back to them. We're not here to take anyone's patients.

Scientific references

  1. Niewald M, Wenzlawowicz KV, Fleckenstein J, et al. (2018). Risk-adapted radiotherapy for Peyronie's disease. Strahlentherapie und Onkologie.

    Open on PubMed
  2. Incrocci L, Wijnmaalen A, Slob AK, et al. (2008). Low-dose external-beam radiotherapy for early-stage Peyronie's disease. Radiation Oncology.

    Open on PubMed

Contact us to learn more.

Confidential consultations at our Knoxville, Tennessee clinic.

Call (865) 999-5988 Request a Call or Text
Call now Request a call